| Chicago CHW | | | | Lance Lynn vs Kyle Hendricks | |
| New York NYM | | | | Marcus Stroman vs Kyle Gibson | |
| Seattle SEA | | | | Marco Gonzales vs Sem definição | |
| Tampa Bay TB | | | | Ryan Yarbrough vs John Means | |
| Boston BOS | | | | Nathan Eovaldi vs Alek Manoah | |
| Detroit DET | | | | Matt Manning vs Cal Quantrill | |
| Pittsburgh PIT | | | | JT Brubaker vs Wade Miley | |
| Washington WSH | | | | Erick Fedde vs Touki Toussaint | |
| Minnesota MIN | | | | Bailey Ober vs Zack Greinke | |
| San Francisco SF | | | | Logan Webb vs Corbin Burnes | |
| Kansas City KC | | | | Mike Minor vs Kwang Hyun Kim | |
| Miami MIA | | | | Sandy Alcantara vs Austin Gomber | |
| Texas TEX | | | | Mike Foltynewicz vs Chris Bassitt | |
| Los Angeles LAA | | | | Patrick Sandoval vs David Price | |
| Arizona ARI | | | | Caleb Smith vs Ryan Weathers | |
