Classificação USLC 2021
| Pacific | J | V | E | D | SG | PTS |
|---|---|---|---|---|---|---|
| Phoenix Rising FC | 30 | 20 | 5 | 5 | +33 | 65 |
| San Diego Loyal SC | 30 | 14 | 5 | 11 | +9 | 47 |
| Orange County SC | 30 | 13 | 7 | 10 | +5 | 46 |
| LA Galaxy II | 30 | 11 | 6 | 13 | 0 | 39 |
| Oakland Roots | 30 | 9 | 8 | 13 | -9 | 35 |
| Tacoma Defiance | 30 | 9 | 8 | 13 | -5 | 35 |
| Sacramento Republic FC | 30 | 8 | 10 | 12 | -6 | 34 |
| Las Vegas Lights FC | 30 | 6 | 3 | 21 | -34 | 21 |
| Mountain | J | V | E | D | SG | PTS |
| El Paso Locomotive FC | 30 | 17 | 10 | 3 | +21 | 61 |
| Colorado Springs Switchbacks FC | 31 | 13 | 10 | 8 | +13 | 49 |
| San Antonio FC | 30 | 13 | 9 | 8 | +9 | 48 |
| New Mexico United | 30 | 11 | 10 | 9 | +4 | 43 |
| Austin Bold FC | 30 | 10 | 10 | 10 | -10 | 40 |
| Rio Grande Valley FC Toros | 29 | 10 | 8 | 11 | 0 | 38 |
| Real Monarchs SLC | 30 | 5 | 7 | 18 | -24 | 22 |
| Central | J | V | E | D | SG | PTS |
| Birmingham Legion FC | 30 | 17 | 6 | 7 | +15 | 57 |
| Louisville City FC | 30 | 16 | 7 | 7 | +21 | 55 |
| Memphis 901 FC | 29 | 12 | 8 | 9 | +3 | 44 |
| FC Tulsa | 29 | 13 | 4 | 12 | 0 | 43 |
| Oklahoma City Energy FC | 30 | 8 | 13 | 9 | -2 | 37 |
| Atlanta United 2 | 32 | 8 | 10 | 14 | -9 | 34 |
| Indy Eleven | 30 | 9 | 7 | 14 | -12 | 34 |
| Sporting Kansas City II | 30 | 4 | 8 | 18 | -24 | 20 |
| AT | J | V | E | D | SG | PTS |
| Tampa Bay Rowdies | 30 | 21 | 2 | 7 | +30 | 65 |
| Charlotte Independence | 30 | 17 | 4 | 9 | +20 | 55 |
| Pittsburgh Riverhounds | 30 | 15 | 7 | 8 | +16 | 52 |
| Miami FC | 30 | 14 | 7 | 9 | +10 | 49 |
| Charleston Battery | 29 | 10 | 7 | 12 | -4 | 37 |
| Hartford Athletic | 30 | 11 | 4 | 15 | -2 | 37 |
| New York Red Bulls II | 30 | 6 | 7 | 17 | -26 | 25 |
| Loudoun United FC | 29 | 4 | 3 | 22 | -42 | 15 |